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1

Synthesis and Structure−Activity Relationships of 3,8-Diazabicyclo[4.2.0]octane Ligands, Potent Nicotinic Acetylcholine Receptor Agonists

Frost (née Pac, Jennifer M., Bunnelle, William H., Tietje, Karin R., Anderson, David J., Rueter, Lynne E., Curzon, Peter, Surowy, Carol S., Ji, Jianquo, Daanen, Jerome F., Kohlhaas, Kathy L.

Journal:

Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 236 KB

english, 2006

2

Predictive validity of a MK-801-induced cognitive impairment model in mice: Implications on the potential limitations and challenges of modeling cognitive impairment associated with schizophrenia preclinically

Brown, Jordan W., Rueter, Lynne E., Zhang, Min

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Année:

2014

Langue:

english

Fichier:

PDF, 698 KB

english, 2014

3

Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia

Lynne E. Rueter, Michael E. Ballard, Kelly B. Gallagher, Ana Maria Basso, Peter Curzon, Kathy L. Kohlhaas

Journal:

Psychopharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 222 KB

english, 2004

4

A Critical Review of 5-HT Brain Microdialysis and Behavior

Rueter, Lynne E., Fornal, Casimir A., Jacobs, Barry L.

Journal:

Reviews in the Neurosciences

Année:

1997

Langue:

english

Fichier:

PDF, 3.24 MB

english, 1997

5

In vivo electrophysiological assessment of the agonistic properties of flibanserin at pre- and postsynaptic 5-HT1A receptors in the rat brain

Lynne E. Rueter, Claude De Montigny, Pierre Blier

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 251 KB

english, 1998

6

Neuronal Release of Serotonin in the Cerebellum of Behaving Rats: An In Vivo Microdialysis Study

Anna Mendlin, Francisco J. Martín, Lynne E. Rueter, Barry L. Jacobs

Journal:

Journal of Neurochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 696 KB

english, 1996

7

Structural abnormalities revealed by magnetic resonance imaging in rats prenatally exposed to methylazoxymethanol acetate parallel cerebral pathology in schizophrenia

Chih-Liang Chin, Peter Curzon, Annette J. Schwartz, Elizabeth M. O'Connor, Lynne E. Rueter, Gerard B. Fox, Mark Day, Ana M. Basso

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.72 MB

english, 2011

8

The drug-induced helplessness test: an animal assay for assessing behavioral despair in response to neuroleptic treatment

Michael E. Ballard, Ana M. Basso, Kelly B. Gallagher, Kaitlin E. Browman, Gerard B. Fox, Karla U. Drescher, Gerhard Gross, Michael W. Decker, Lynne E. Rueter, Min Zhang

Journal:

Psychopharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 209 KB

english, 2007

9

The scopolamine model as a pharmacodynamic marker in early drug development

Robert A. Lenz, Jeffrey D. Baker, Charles Locke, Lynne E. Rueter, Eric G. Mohler, Keith Wesnes, Walid Abi-Saab, Mario D. Saltarelli

Journal:

Psychopharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 338 KB

english, 2012

10

Post-adoption contact, adoption communicative openness, and satisfaction with contact as predictors of externalizing behavior in adolescence and emerging adulthood

Harold D. Grotevant, Martha Rueter, Lynn Von Korff, Christopher Gonzalez

Journal:

Journal of Child Psychology and Psychiatry

Année:

2011

Langue:

english

Fichier:

PDF, 148 KB

english, 2011

11

Mammalian brain dihydrofolate reductase

R. Lynn, M. E. Rueter, R. W. Guynn

Journal:

Journal of Neurochemistry

Année:

1977

Langue:

english

Fichier:

PDF, 206 KB

english, 1977

12

A-85380: A Pharmacological Probe for the Preclinical and Clinical Investigation of the α4β2 Neuronal Nicotinic Acetylcholine Receptor

Lynne E. Rueter, Diana L. Donnelly-Roberts, Peter Curzon, Clark A. Briggs, David J. Anderson, Robert S. Bitner

Journal:

CNS Drug Reviews

Année:

2006

Langue:

english

Fichier:

PDF, 126 KB

english, 2006

13

ABT-089: Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders

Lynne E. Rueter, David J. Anderson, Clark A. Briggs, Diana L. Donnelly-Roberts, Gary A. Gintant, Murali Gopalakrishnan, Nan-Horng Lin, Mark A. Osinski, Glenn A. Reinhart, Michael J. Buckley, Ruth L. M

Journal:

CNS Drug Reviews

Année:

2004

Langue:

english

Fichier:

PDF, 150 KB

english, 2004

14

Electrophysiological examination of the effects of sustained flibanserin administration on serotonin receptors in rat brain

Lynne E Rueter, Pierre Blier

Journal:

British Journal of Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 550 KB

english, 1999

15

Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

Kathy L. Kohlhaas, Robert S. Bitner, Murali Gopalakrishnan, Lynne E. Rueter

Journal:

Psychopharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 357 KB

english, 2012

16

A-366833: A novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane α4β2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models

Jianguo Ji, William H. Bunnelle, David J. Anderson, Connie Faltynek, Tino Dyhring, Philip K. Ahring, Lynne E. Rueter, Peter Curzon, Michael J. Buckley, Kennan C. Marsh, Anita Kempf-Grote, Michael D. M

Journal:

Biochemical Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 720 KB

english, 2007

17

The use of the scopolamine-induced cognitive impairment model to translate on-target activity for ABT-894 from rodents/monkeys to humans: Preclinical evidences

Lynne E. Rueter, Ana L. Rêlo, Marcel M. van Gaalen, Michael E. Ballard, Alvin V. Terry Jr., Jerry Buccafusco, Min Zhang

Journal:

Biochemical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 53 KB

english, 2011

18

α7 NNR allosteric modulation in behavioral models of cognition

Kathy L. Kohlhaas, Holly Robb, Victoria Roderwald, Stella Markosyan, Katherine Salte, Robert S. Bitner, Eric Mohler, Alvin V. Terry, Jerry Buccafusco, Lynne E. Rueter, Lance Lee, Murali Gopalakrishnan

Journal:

Biochemical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 57 KB

english, 2011

19

Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug–drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs

Min Zhang, Michael E. Ballard, Liping Pan, Stanley Roberts, Ramin Faghih, Marlon Cowart, Tim A. Esbenshade, Gerard B. Fox, Michael W. Decker, Art A. Hancock, Lynne E. Rueter

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 313 KB

english, 2005

20

Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease

Nathan R. Rustay, Elizabeth A. Cronin, Peter Curzon, Stella Markosyan, Robert S. Bitner, Teresa A. Ellis, Jeffrey F. Waring, Michael W. Decker, Lynne E. Rueter, Kaitlin E. Browman

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2010

21

Spinal mechanisms underlying A-85380-induced effects on acute thermal pain

Lynne E. Rueter, Michael D. Meyer, Michael W. Decker

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 580 KB

english, 2000

22

A microdialysis examination of serotonin release in the rat forebrain induced by behavioral/environmental manipulations

Lynne E. Rueter, Barry L. Jacobs

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 2.39 MB

english, 1996

23

The identification of novel structural compound classes exhibiting high affinity for neuronal nicotinic acetylcholine receptors and analgesic efficacy in preclinical models of pain

Michael D. Meyer, Michael W. Decker, Lynne E. Rueter, David J. Anderson, Michael J. Dart, Ki H. Kim, James P. Sullivan, Michael Williams

Journal:

European Journal of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 989 KB

english, 2000

24

Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan

Kaitlin E Browman, Victoria A Komater, Peter Curzon, Lynne E Rueter, Arthur A Hancock, Michael W Decker, Gerard B Fox

Journal:

Behavioural Brain Research

Année:

2004

Langue:

english

Fichier:

PDF, 234 KB

english, 2004

25

Effects of antipsychotics and selective D3 antagonists on PPI deficits induced by PD 128907 and apomorphine

Min Zhang, Michael E. Ballard, Liliane V. Unger, Andreas Haupt, Gerhard Gross, Michael W. Decker, Karla U. Drescher, Lynne E. Rueter

Journal:

Behavioural Brain Research

Année:

2007

Langue:

english

Fichier:

PDF, 266 KB

english, 2007

26

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders

Ana M. Basso, Natalie A. Bratcher, Richard R. Harris, Michael F. Jarvis, Michael W. Decker, Lynne E. Rueter

Journal:

Behavioural Brain Research

Année:

2009

Langue:

english

Fichier:

PDF, 465 KB

english, 2009

27

Behavioral characterization of a mutant mouse strain lacking d-amino acid oxidase activity

Min Zhang, Michael E. Ballard, Ana M. Basso, Natalie Bratcher, Kaitlin E. Browman, Pete Curzon, Ryuichi Konno, Axel H. Meyer, Lynne E. Rueter

Journal:

Behavioural Brain Research

Année:

2011

Langue:

english

Fichier:

PDF, 249 KB

english, 2011

28

Vogel conflict test: Sex differences and pharmacological validation of the model

Ana M. Basso, Kelly B. Gallagher, Joseph P. Mikusa, Lynne E. Rueter

Journal:

Behavioural Brain Research

Année:

2011

Langue:

english

Fichier:

PDF, 382 KB

english, 2011

29

Loss of functional neuronal nicotinic receptors in dorsal root ganglion neurons in a rat model of neuropathic pain

Gilles R. Dubé, Kathy L. Kohlhaas, Lynne E. Rueter, Carol S. Surowy, Michael D. Meyer, Clark A. Briggs

Journal:

Neuroscience Letters

Année:

2005

Langue:

english

Fichier:

PDF, 138 KB

english, 2005

30

Peripheral and central sites of action for A-85380 in the spinal nerve ligation model of neuropathic pain

Lynne E Rueter, Kathy L Kohlhaas, Peter Curzon, Carol S Surowy, Michael D Meyer

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 303 KB

english, 2003

31

ABT-594 improves performance in the 5-choice serial reaction time task under conditions of increased difficulty, sub-chronic dosing, and in poorly-performing subjects

Eric G. Mohler, Stanley R. Franklin, Lynne E. Rueter, Gerard B. Fox, Michael W. Decker, Kaitlin E. Browman

Journal:

Pharmacology Biochemistry and Behavior

Année:

2010

Langue:

english

Fichier:

PDF, 893 KB

english, 2010

32

Improving the therapeutic window in the treatment of pain with nicotinic ligands

Lynne E. Rueter, Michael W. Decker, Robert S. Bitner

Journal:

Drug Discovery Today: Therapeutic Strategies

Année:

2004

Langue:

english

Fichier:

PDF, 222 KB

english, 2004

33

NEONATAL TREATMENT WITH METHYLAZOXYMETHANOL ACETATE (MAM) AS A NEURODEVELOPMENTAL MODEL OF SCHIZOPHRENIA: BEHAVIORAL, PHARMACOLOGICAL AND MORPHOLOGICAL CHARACTERIZATION

Ana M. Basso, Peter Curzon, Min Zhang, Kelly B. Gallagher, Katherine Salte, Jordan Brown, Arthur L. Nikkel, R. Scott Bitner, Mark Day, Michael W. Decker, Gerard B. Fox, Lynne E. Rueter, Chih-Liang Chi

Journal:

Schizophrenia Research

Année:

2010

Langue:

english

Fichier:

PDF, 77 KB

english, 2010

34

The scopolamine-induced deficit model is a viable translational approach that can expedite decision making in clinical development: Preclinical evidence

Rueter, Lynne E., Browman, Kaitlin E., Buccafusco, Jerry J., Buckley, Michael J., Decker, Michael W.

Journal:

Alzheimer's & Dementia

Année:

2009

Langue:

english

Fichier:

PDF, 72 KB

english, 2009

35

Discriminative-stimulus effects of NS9283, a nicotinic α4β2* positive allosteric modulator, in nicotine-discriminating rats

Mohler, Eric G., Franklin, Stanley R., Rueter, Lynne E.

Journal:

Psychopharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 262 KB

english, 2014

36

Nicotinic modulation of auditory evoked potential electroencephalography in a rodent neurodevelopmental model of schizophrenia

Kohlhaas, Kathy L., Robb, Holly M., Roderwald, Victoria A., Rueter, Lynne E.

Journal:

Biochemical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 369 KB

english, 2015

37

Effect of Dopamine D3 Antagonists on PPI in DBA/2J Mice or PPI Deficit Induced by Neonatal Ventral Hippocampal Lesions in Rats

Zhang, Min, Ballard, Michael E, Kohlhaas, Kathy L, Browman, Kaitlin E, Jongen-Rêlo, Ana-Lucia, Unger, Liliane V, Fox, Gerard B, Gross, Gerhard, Decker, Michael W, Drescher, Karla U, Rueter, Lynne E

Journal:

Neuropsychopharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 420 KB

english, 2006

38

Antidepressant-Like Effect of D2/3 Receptor-, but not D4 Receptor-Activation in the Rat Forced Swim Test

Basso, Ana M, Gallagher, Kelly B, Bratcher, Natalie A, Brioni, Jorge D, Moreland, Robert B, Hsieh, Gin C, Drescher, Karla, Fox, Gerard B, Decker, Michael W, Rueter, Lynne E

Journal:

Neuropsychopharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 258 KB

english, 2005

39

Cross-site strain comparison of pharmacological deficits in the touchscreen visual discrimination test

Mohler, Eric G., Ding, Zhiyong, Rueter, Lynne E., Chapin, Douglas, Young, Damon, Kozak, Rouba

Journal:

Psychopharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2015

40

Preclinical evaluation of non-imidazole histamine H3 receptor antagonists in comparison to atypical antipsychotics for the treatment of cognitive deficits associated with schizophrenia

Brown, Jordan W., Whitehead, Caroline A., Basso, Ana M., Rueter, Lynne E., Zhang, Min

Journal:

The International Journal of Neuropsychopharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 217 KB

english, 2013

41

Anticonvulsant effects of structurally diverse GABAB positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model

Brown, Jordan W., Moeller, Achim, Schmidt, Martin, Turner, Sean C., Nimmrich, Volker, Ma, Junli, Rueter, Lynne E., van der Kam, Elizabeth, Zhang, Min

Journal:

Neuropharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2016

42

Nicotinic modulation of auditory evoked potential electroencephalography in a rodent neurodevelopmental model of schizophrenia

Kohlhaas, Kathy L., Robb, Holly M., Roderwald, Victoria A., Rueter, Lynne E.

Journal:

Biochemical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 191 KB

english, 2015

43

Treating the Cognitive Deficits of Schizophrenia with Alpha4Beta2 Neuronal Nicotinic Receptor Agonists

Radek, Richard, Kohlhaas, Kathy, Rueter, Lynne, Mohler, Eric

Journal:

Current Pharmaceutical Design

Année:

2010

Langue:

english

Fichier:

PDF, 437 KB

english, 2010

44

Changes in forebrain serotonin at the light-dark transition

Rueter, Lynne E., Jacobs, Barry L.

Journal:

Année:

1996

Fichier:

PDF, 339 KB

1996

45

Profiling attention and cognition enhancing drugs in a rat touchscreen-based continuous performance test

Ding, Zhiyong, Brown, Jordan W., Rueter, Lynne E., Mohler, Eric G.

Journal:

Psychopharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2018